An internationally recognized researcher Dr. By Dr. Kahn at the University of Louisville and educated at Washington University and the National Institutes of Health, where he most recently served as Head of Department of Cellular and Molecular Physiology of the Diabetes Unit.
In 2007 he was appointed Vice Chair of the Board of Trustees Joslin. Kahn has the highest scientific awards of the American Diabetes Association, U.S. Endocrine Society, British Diabetes and Endocrine Societies Working Group thatesearch Foundation, International Diabetes Federation and American Federation for Clinical Research, and many other honors, including election to the National Academy of Sciences and the Institute of Medicine.Illuminating imbalanceThe membrane protein is from a thermophilic bacterium. Compared to existing structures announced TM287/288 has two distinct protein chains, which assemble at a heterodimer. About half of the 40 human ABC transporter are heterodimers. The discovery asymmetry allow us role of role of the ABC transporters in a different light, says snap. In the longer term, our results could be used to develop new drugs against multi-resistant bacteria and tumors They also make difficult to treat. They also make new approaches to recovery or alleviation possible to hereditary, concludes size?
Despite its importance in the biology and medical, does not have been unscrambled the atomic structures of a few ABC transporters. Now, under the guidance of Markus snap and Professor Markus Gr? About half the Michael Hohl and lead scientist Christophe M. Briand in Rissen in the atomic structure of the new ABC transporters ‘TM287/288 ‘successful.