Developed another Hopkins researchers in the Department of Psychiatry and Behavioral Sciences

The study was conducted in the laboratory of Mikhail Pletnikov conducted in the Department of Psychiatry and Behavioral Sciences .Last month, developed another Hopkins researchers in the Department of Psychiatry and Behavioral Sciences, Akira Sawa, and his team, a similar mutant DISC-1 mouse model of schizophrenia. Pletnikov which is the first model in which researchers can control the expression of this mutated gene, and the model illuminates other aspects of the biology of the disease. Study, which appearsurn the mutant DISC – 1 gene, the mice by a non-toxic chemical that is a genetic switching mechanism is control the production of DISC – 1 protein in turn.

the idea the idea that schizophrenia is a disease associated with abnormal brain development, says senior co-author of the study, Christopher Ross, of the Department of Psychiatry and Behavioral Sciences. And in a position to regulate the timing of the expression of the mutated protein makes it possible to the timing the timing and mechanism of specific abnormalities – a tool that to the discovery to the discovery of drugs that could potentially control or disease. disease. .

Ronin also found in the areas of the brain such as the hippocampus and the Purkinje cells of the cerebellum.

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