IPI-504 preferentially targets and accumulates in tumor tissues tadalafil and sildenafil.

IPI-504 preferentially targets and accumulates in tumor tissues, sparing healthy tissue tadalafil and sildenafil . In preclinical studies, it a broad potential a broad potential to treat certain types of cancer, both as a a monotherapy and in combination with existing anti-cancer drugs. The water-based formulation of IPI-504 is useful to provide an intravenous infusion. Infinity is currently conducting two Phase 1 clinical trials of intravenous formulations of IPI-504. In July 2005, Infinity initiated the first of its Phase 1 clinical trials in refractory multiple myeloma. In December 2005, Infinity initiated the second Phase 1 clinical trials of IPI-504 in refractory gastrointestinal stromal tumors . Infinity has also begun developing an oral formulation of IPI-504, if successful, could be a more convenient route of administration for cancer therapy.

‘MedImmune in oncology in oncology as an important therapeutic area by advancing and expanding its product pipeline targeting various cancers ASH acceptance of seven scientific presentations by MedImmune and its partners also means,’commented Dirk Reitsma, MedImmune vice president, Clinical Development, Oncology. Data will be presented at ASH, are:.

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