There exists a huge caveat because aldosterone will not get into the mind terribly well. Other good news emerging is certainly that adolesterone blockers, such as for example spironolactone and a newer, more specific blocker eplerenone, can help convert the tide. Spironolactone was developed as an antihypertensive years back but didn’t work nicely, Dr. Dorrance says. Then, a University of Michigan study in the mid-1980s showed heart failure individuals who got the drug in addition to standard treatment, such as for example beta blockers and ACE inhibitors, stopped dying basically, says Dr.Marcelis, Ph.D., Christine E. De Die-Smulders, M.D., Ph.D., Janine Milbradt, B.S., Anton A. Franken, M.D., Ph.D., Arjan J. Harsevoort, M.S., Klaske D. Lichtenbelt, M.D., Hans E. Pruijs, M.D., Ph.D., M. Estela Rubio-Gozalbo, M.D., Ph.D., Rolf Zwertbroek, M.D., Youssef Moutaouakil, M.S., Jaqueline Egthuijsen, M.S., Matthias Hammerschmidt, Ph.D., Renate Bijman, B.S., Cor M. Semeins, M.S., Astrid D. Bakker, Ph.D., Vincent Everts, Ph.D., Jenneke Klein-Nulend, Ph.D., Natalia Campos-Obando, M.D., Albert Hofman, M.D., Ph.D., Gerard J. Te Meerman, Ph.D., Annemieke J.M.H. Verkerk, Ph.D. Uitterlinden, Ph.D., Alessandra Maugeri, Ph.D., Erik A. Sistermans, Ph.D., Quinten Waisfisz, Ph.D., Hanne Meijers-Heijboer, M.D., Ph.D., Brunhilde Wirth, Ph.D., Marleen E.H.