There is a nonsignificant trend toward the development of more squamous-cell carcinomas in the nicotinamide group than in the placebo group in the 6-month postintervention period . The amount of actinic keratoses was 11 percent low in the nicotinamide group than in the placebo group at 3 months , 14 percent lower at six months , 20 percent lower at 9 months , and 13 percent lower in 12 months . This equated to three to five 5 fewer actinic keratoses, typically, from the baseline count in the nicotinamide group than in the placebo group . The rate of sunscreen use in the week before baseline and at the 3-month visits through 12 months was lower in the nicotinamide group than in the placebo group . Safety No clinically significant between-group distinctions were found with respect to the number or types of adverse occasions that occurred in the analysis groups .Don’t bring them inside with you after you’ve been outside. Once you return home, remove your shoes and have a quick shower. ‘With a particularly tough allergy season anticipated this year, we’re proud to partner with AAFA and Dr. Linda Dahl to supply a helpful community and source for our energetic Puff fans and followers,’ said Laura Dressman, Puffs Face Tissues. ‘It was an all natural fit to synergy with Puffs this allergy period,’ said Mike Tringale, Vice President of External Affairs for AAFA.